Tissue, system and organ physiology Glutamatergic, cholinergic and GABAergic neurons contribute to the septohippocampal pathway and exhibit distinct electrophysiological properties: novel implications for hippocampal rhythmicity
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چکیده
Glutamatergic, cholinergic and GABAergic neurons contribute to the septohippocampal pathway and exhibit distinct electrophysiological properties: novel implications for hippocampal rhythmicity.
منابع مشابه
Wang Loop Synchronization in the Septohippocampal Reciprocal Pacemaker Neurons for the Theta Rhythm and Their
[PDF] [Full Text] [Abstract] , May 1, 2003; 89 (5): 2538-2554. J Neurophysiol M. J. E. Richardson, N. Brunel and V. Hakim From Subthreshold to Firing-Rate Resonance [PDF] [Full Text] [Abstract] , September 15, 2003; 551 (3): 927-943. J. Physiol. F. Sotty, M. Danik, F. Manseau, F. Laplante, R. Quirion and S. Williams septohippocampal neurons: novel implications for hippocampal rhythmicity Di...
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The Cholinergic and GABAergic .bers of the medial septal/diagonal band of Broca (MS/DB) area project to the hippocampus and constitute the septo-hippocampal pathway, which has been proven to play a role in learning and memory. In addition, the hippocampus has bidirectional connections with the septum so that to self-regulate of cholinergic input. The activity of septal and hippocampal neuron...
متن کاملGlutamatergic neurons of the mouse medial septum and diagonal band of Broca synaptically drive hippocampal pyramidal cells: relevance for hippocampal theta rhythm.
Neurons of the medial septum and diagonal band of Broca (MS-DBB) provide an important input to the hippocampus and are critically involved in learning and memory. Although cholinergic and GABAergic MS-DBB neurons are known to modulate hippocampal activity, the role of recently described glutamatergic MS-DBB neurons is unknown. Here, we examined the electrophysiological properties of glutamaterg...
متن کاملAcetylcholinesterase inhibitors activate septohippocampal GABAergic neurons via muscarinic but not nicotinic receptors.
Acetylcholinesterase (AChE) inhibitors, which increase synaptic levels of available acetylcholine (ACh) by preventing its degradation, are the most extensively prescribed drugs for the treatment of Alzheimer's disease. In animals, AChE inhibitors improve learning and memory, reverse scopolamine-induced amnesia, and produce hippocampal theta rhythm. The medial septum/diagonal band of Broca (MSDB...
متن کاملMuscarinic tone sustains impulse flow in the septohippocampal GABA but not cholinergic pathway: implications for learning and memory.
Systemic infusions of the muscarinic cholinergic receptor antagonists atropine and scopolamine (atr/scop) produce an amnesic syndrome in humans, subhuman primates, and rodents. In humans, this syndrome may resemble early symptoms of Alzheimer's disease. Behavioral studies in rats have demonstrated that the medial septum/diagonal band of Broca (MSDB), which sends cholinergic and GABAergic projec...
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تاریخ انتشار 2003